blood glucose — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T34532	Sari 59-801	Sari-59-801	Others
	Sari 59-801 is a novel, orally effective hypoglycemic compound.		Others
T10492	BD-AcAc 2	Ketone Ester	Reactive Oxygen Species
	BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones. BD-AcAc 2 can elevate plasma levels of acetoacetate and β-hydroxybutyrate, blood Na+, blood glucose levels and blood...		Reactive Oxygen Species
T0214	Pioglitazone	U 72107	Ferroptosis , PPAR
	Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury.		Ferroptosis , PPAR
T3675	1-Deoxynojirimycin	Duvoglustat,Moranoline,moranolin	PI3K , Glucosidase
	1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.		PI3K , Glucosidase
T21344	1-Deoxynojirimycin hydrochloride	Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin	PI3K , Antibacterial , Antibiotic , Glucosidase
	1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.		PI3K , Antibacterial , Antibiotic , Glucosidase
T5S0669	Bergamottin	5-Geranoxypsoralen,Bergamotine,Bergaptin	P450
	1. Bergamottin (5-Geranoxypsoralen) can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A^ydiabetic mice.		P450
T4396	Officinalisinin I		Others
	Officinalisinin I can effectively reduce the blood glucose and protect nerve injuryin diabetic mice.		Others
T30142	ARRY-403	AMG-151,ARRY 403,ARRY403,ARRY-403,AMG151,AMG 151	Glucokinase
	ARRY-403 is a novel glucokinase activator that reduces fasting and postprandial blood glucose in patients with type 2 diabetes.		Glucokinase
T4726	D-Glucose 6-phosphate sodium	G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate	Others , Endogenous Metabolite
	In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the begi...		Others , Endogenous Metabolite
T22708	Darglitazone	CP-86325	PPAR
	Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism.		PPAR
T14212	AMG-1694		Glucokinase
	AMG-1694, a potent disruptor of the glucokinase–glucokinase regulatory protein (GK-GKRP) complex, operates by promoting the dissociation of this complex, thereby indirectly enhancing GK enzymatic activity with an IC50 of...		Glucokinase
T5735	Methyl deacetylasperulosidate	Deacetyl asperulosidic acid methyl ester,6α-Hydroxygeniposide	Others
	Methyl deacetylasperulosidate (6α-Hydroxygeniposide) is a natual product isolated from the herbs of Hedyotis diffusa Willd,it can lower the blood glucose level in normal mice.		Others
T1782L	Canagliflozin hemihydrate	JNJ28431754,TA 7284,TA7284,TA-7284,JNJ 28431754,JNJ-28431754	SGLT
	Canagliflozin hemihydrate (TA 7284) is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reab...		SGLT
T67728	α-Glucosidase-IN-23		Glucosidase
	α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 can decrease blood glucose by α-glucosidase inhibition (IC50= 4.48 μM).		Glucosidase
T77781	Lotiglipron	PF-07081532	Glucagon Receptor
	Lotiglipron (PF-07081532) is an orally active and potent GLP-1R agonist that reduces blood glucose and body weight and may be useful in the study of type 2 diabetes mellitus (T2DM) and obesity.		Glucagon Receptor
T8818	TC-G 1005		GPCR19
	TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.		GPCR19
T63166	LSN3318839	LSN-3318839,LSN 3318839	Glucagon Receptor
	LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can be used to lower blood glucose.		Glucagon Receptor
T3332	Isosteviol	(-)-Isosteviol	IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase
	Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio...
T16083	Mizagliflozin	GSK-1614235 free base,KGA-3235 free base,DSP-3235 free base	SGLT
	Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that ca...		SGLT
T6587	Mitiglinide Calcium	KAD-1229,S21403	ATPase , Potassium Channel
	Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.		ATPase , Potassium Channel